Brand name:
Serevent
Pronounced: SER-ah-vent
Generic name: Salmeterol xinafoate
Other brand name: Serevent Diskus
Why is Serevent prescribed?
Serevent relaxes the muscles in the walls of the bronchial tubes,
allowing the passageways to expand and carry more air. Taken regularly
(twice a day), the drug is used in the treatment of asthma and chronic
obstructive pulmonary disease (COPD) including emphysema and chronic
bronchitis. A relatively long-acting medication, it is recommended
only for the type of asthma patient who needs shorter-acting bronchodilators
such as Alupent and Ventolin on a frequent, regular basis.
Serevent is available in an aerosol inhaler and as Serevent Diskus
inhalation powder. Both forms of Serevent can be used with or without
inhaled or oral steroid therapy.
Most important fact about Serevent
Serevent is intended only for long-term prevention of symptoms, and
should not be used more than twice a day. Do not use it to treat acute
asthma attacks, and do not attempt to relieve worsening asthma by increasing
the frequency of your doses. (Your local doctor will prescribe a short-acting
bronchodilator to relieve acute attacks.)
Seriously worsening asthma is a dangerous-even life-threatening-condition
that needs immediate medical attention. Alert your local doctor if your short-acting
bronchodilator is becoming less effective or you need more inhalations
than usual. Also consider it a warning sign if you need 4 or more inhalations
daily for 2 days or more in a row, or find that you are finishing a
200-dose canister in less than 8 weeks.
How should you take Serevent?
Use no more than the prescribed dose and follow package directions
closely. Space your two daily doses approximately 12 hours apart, in
the morning and evening. To be effective, the drug must be used regularly
every day.
Serevent aerosol inhaler must be shaken thoroughly before each use.
Test-spray the inhaler 4 times before the first use and whenever 4
weeks have passed since the last use. Avoid spraying in the eyes.Serevent
Diskus should never be used with a spacer. Always activate the Diskus
device in a level, horizontal position. Never exhale into
the Diskus device, and always keep it dry. Do not wash the mouthpiece
or any other part of the device. Never attempt to take the Diskus apart.You
may be able to taste or feel Serevent delivered by the Diskus. However,
whether you can sense the delivery of a dose or not, never
take more inhalations than what your local doctor prescribes.
Serevent side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your local doctor as soon as possible. Only your local doctor can determine
if it is safe for you to continue using Serevent.
* Side effects may include:
Asthma, back pain, bronchitis, chest congestion, cough, diarrhea, dizziness,
headache, nasal inflammation, pallor, respiratory tract infection, sinus
headache, sinus infection, sinus problems, sore throat, stomachache, tremor
Why should Serevent not be prescribed?
If Serevent gives you an allergic reaction, you cannot continue using
it.
Special warnings about SereventSerevent is not for the treatment of
seriously worsening asthma, and should not be started if your asthma
is deteriorating.If you are taking inhaled or oral steroid medications
for your asthma, continue using them along with Serevent. This drug
does not replace
them.A safety study found that one of the ingredients in Serevent,
salmeterol, may be associated with rare cases of serious asthma attacks
or asthma-related
death. If you're concerned, talk with the local doctor about your options.
Do not, however, stop using Serevent without first consulting your
local doctor.Very rarely, Serevent has triggered allergic reactions in people
with severe milk allergy. If you develop an allergic reaction (throat
irritation,
choking, hives, face and throat swelling, rash, and wheezing) after
using Serevent, call your local doctor immediately. Likewise, if symptoms
of asthma or chronic lung disease get worse after inhaling Serevent,
stop using it, take a short-acting bronchodilator, and check with your
local doctor at once.Although such effects are rare, Serevent can cause an
increase in blood pressure and heart rate. Use Serevent carefully if
you have high
blood pressure, heart disease, or an irregular heartbeat. Caution is
also advised if you have a seizure disorder or an overactive thyroid.Serevent
aerosol inhaler can be given to children 12 years of age and older.
The Diskus inhalation powder can be given to children 4
and older.Do not stop Serevent therapy without a local doctor's guidance.
Your symptoms could worsen without Serevent.
Possible food and drug interactions when taking Serevent
If Serevent is taken with certain other drugs, the effects of either
drug could be increased, decreased, or altered. It is especially important
to check with your local doctor before combining Serevent with the following:
Airway-opening medications such as Alupent, Proventil, and Ventolin
Blood pressure medications known as beta blockers, including Inderal,
Lopressor, and Tenormin
MAO inhibitors such as the antidepressants Marplan, Nardil, and Parnate
Tricyclic antidepressants such as Elavil and Tofranil
Water pills (diuretics) such as furosemide (Lasix) and hydrochlorothiazide
(HydroDIURIL)
Special information if you are pregnant or breastfeedingSerevent has
not been adequately tested in pregnant women and is recommended only
if its benefits clearly outweigh potential risks. Check with your
local doctor immediately if you are pregnant or are planning a pregnancy.
Serevent's effects during breastfeeding are also unknown. You and your
local doctor should decide whether to discontinue nursing or give up
Serevent.
Recommended dosage for Serevent AEROSOL
INHALER
Any medication taken in excess can have serious consequences. If you
suspect an overdose, seek medical attention immediately.* Symptoms
of Serevent overdose may include:
Angina (chest pain), dizziness, dry
mouth, fatigue, flu-like symptoms, headache, heart irregularities,
high or low blood
pressure, high blood
sugar, insomnia,
muscle cramps, nausea, nervousness, rapid heartbeat, seizures, tremor
If you miss a dose...
Take it as soon as you remember. If it is almost time for your next
dose, skip the one you missed and go back to your regular schedule.
Never double your dose.
Storage instructions...
Store the Serevent aerosol inhaler and Serevent Diskus at room temperature
away from direct sunlight and freezing temperatures. Leave the aerosol
inhaler canister with the nozzle end down. Keep the Diskus in a dry
place. Throw away the Diskus inhalation device after every blister
has been used (when the dose indicator reads "0") or 6 weeks
after the blisters have been removed from their foil pouch.
