Brand
name: Moduretic
Pronounced: mod-your-ET-ik
Generic ingredients: Amiloride, Hydrochlorothiazide
Why is Moduretic prescribed?
Most important fact about Moduretic
If you have high blood pressure, you must take Moduretic regularly
for it to be effective. Since blood pressure declines gradually, it
may be several weeks before you get the full benefit of Moduretic;
and you must continue taking it even if you are feeling well. Moduretic
does not cure high blood pressure; it merely keeps it under control.
How should you take Moduretic without prescriptions?
Take Moduretic with food.
Take Moduretic exactly as prescribed by your doctor. Stopping Moduretic
suddenly could cause your condition to worsen.
If you miss a dose...
Take the forgotten dose as soon as you remember. If it is almost time
for your next does, skip the one you missed and go back to your regular
schedule. Never take a double dose.
Storage instructions...
Store at room temperature. Keep Moduretic in the container it came
in, tightly closed, and protected from moisture, light, and freezing.
Moduretic side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking Moduretic.
* Side effects may include:
Diarrhea, dizziness, elevated potassium levels, fatigue, headache, irregular
heartbeat, itching, leg pain, loss of appetite, nausea, rash, shortness of
breath, stomach and intestinal pain, weakness
Why should Moduretic not be prescribed?
If you are unable to urinate or have serious kidney disease, or if
you have high potassium levels in your blood, you should not take Moduretic.
If you are sensitive to or have ever had an allergic reaction to amiloride,
hydrochlorothiazide or similar drugs, or if you are sensitive to other
sulfonamide-derived drugs, you should not take Moduretic. Make sure
your doctor is aware of any drug reactions you may have experienced.
Special warnings about Moduretic
Potassium supplements, potassium-containing salt substitutes, and
other diuretics (such as Dyazide) that minimize loss of potassium should
not be used while you are taking moduretic unless your doctor specifically
says otherwise. You should also limit your consumption of potassium-rich
foods such as bananas, prunes, raisins, orange juice, and whole and
skim milk. Ask your doctor for advice on how much of these foods to
consume.
If you are taking Moduretic, a complete assessment of your kidney
function should be done; kidney function should continue to be monitored.
If you are taking an ACE-inhibitor type of blood pressure medication
such as Vasotec, Moduretic should be used with extreme caution.
If you have liver disease, diabetes, gout, or collagen vascular disease
(lupus erythematosus), Moduretic should be used with caution.
If you have bronchial asthma or a history of allergies, you may be
at risk for an allergic reaction to Moduretic.
Dehydration, excessive sweating, severe diarrhea or vomiting could
deplete your fluids and cause your blood pressure to become too low.
Be careful when exercising and in hot weather.
Notify your doctor or dentist that you are taking Moduretic if you
have a medical emergency or before you have surgery.
Possible food and drug interactions when taking Moduretic
Moduretic may increase the effects of alcohol. Avoid alcohol while
taking Moduretic.
If Moduretic is taken with certain other drugs, the effects of either
could be increased, decreased, or altered. It is especially important
to check with your doctor before combining Moduretic with the following:
ACE inhibitors such as Vasotec
Barbiturates such as phenobarbital
Cholestyramine (Questran)
Colestipol (Colestid)
Corticosteroids such as prednisone
Cyclosporine (Sandimmune, Neoral)
Insulin
Lithium (Eskalith, Lithobid)
Muscle relaxants such as tubocurarine
Narcotics such as Percocet
Nonsteroidal anti-inflammatory drugs such as Naprosyn
Norepinephrine (Levophed)
Oral drugs for treating diabetes such as Micronase, DiaBeta
Other high blood pressure medications
Tacrolimus (Prograf)
Special information if you are pregnant or breastfeeding
The effects of Moduretic during pregnancy have not been adequately
studied. If you are pregnant or plan to become pregnant, inform your
doctor immediately. Moduretic appears in breast milk and could affect
a nursing infant. If Moduretic is essential to your health, your doctor
may advise you to discontinue breastfeeding until your treatment is
finished.
Recommended dosage for Moduretic
Your doctor will tailor the dosage to meet your individual requirements,
taking into consideration other medical conditions you may have and
other medications you may be taking.
ADULTS
Overdosage
Any medication taken in excess can cause symptoms of overdose. If
you suspect an overdose, seek medical attention immediately.
No specific information on symptoms of Moduretic overdose is available,
but dehydration might be expected.
